FETAL DNA (NIPT) TEST IN YALOVA

Safe, Accurate, and Non-Invasive Prenatal Genetic Screening

What Is the NIPT Test?

NIPT (Non-Invasive Prenatal Testing) — also known as the Fetal DNA test or cell-free fetal DNA (cffDNA) — is a highly advanced prenatal screening test that provides early, reliable, and completely safe information about your baby’s genetic health. It analyzes small fragments of fetal DNA circulating in the mother’s blood to detect chromosomal abnormalities without any risk to the mother or baby.

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In Yalova, the NIPT test is offered in collaboration with leading genetic laboratories in Turkey. The sample is collected at local clinics or hospitals and analyzed in accredited laboratories using cutting-edge genetic sequencing technologies. Since it only requires a small blood sample from the mother’s arm, there is no risk of miscarriage or harm — unlike invasive diagnostic procedures such as amniocentesis.

How Does the NIPT Test Work?

During pregnancy, fragments of the baby’s DNA (called cell-free fetal DNA) cross into the mother’s bloodstream from the placenta. These fragments can be analyzed as early as the 10th week of pregnancy.

Yalova-based clinics send the blood sample to partner laboratories equipped with Next Generation Sequencing (NGS) systems. This technology examines each chromosome to identify extra or missing copies that may indicate certain genetic conditions.

The results are typically ready within 7–10 days, and some labs offer express testing options with results available in 3–5 days.

What Conditions Can NIPT Detect?

Common Chromosomal Abnormalities

NIPT accurately screens for the most common chromosomal conditions, including:

Down Syndrome (Trisomy 21): Caused by an extra chromosome 21; detection rate above 99%.
Edwards Syndrome (Trisomy 18): Caused by an extra chromosome 18; detection rate around 97%.
Patau Syndrome (Trisomy 13): Caused by an extra chromosome 13; detection rate above 90%.

Sex Chromosome Abnormalities

The test can also identify conditions linked to sex chromosomes, such as:

Turner Syndrome (45,X)
Klinefelter Syndrome (47,XXY)
Triple X Syndrome (47,XXX)
Jacobs Syndrome (47,XYY)

Extended Genetic Panels

Some genetic laboratories that serve Yalova clinics offer expanded NIPT panels capable of detecting rare genetic conditions such as DiGeorge, Prader-Willi, and Angelman syndromes. Your doctor can advise you on whether this additional screening is appropriate based on your medical and family history.

When Should the NIPT Test Be Performed?

The NIPT test can be done from the 10th week of pregnancy onward. At this stage, fetal DNA in the mother’s bloodstream is high enough for accurate testing. The test remains safe and reliable throughout the second and third trimesters.

Who Should Consider NIPT?

Although NIPT is available to all pregnant women, it is especially recommended for:

Women aged 35 years or older
Pregnancies with abnormal first-trimester screening results
IVF pregnancies or assisted reproduction cases
Families with a history of chromosomal disorders
Expectant mothers with ultrasound findings suggestive of genetic risk
Parents wishing to avoid invasive tests such as amniocentesis
Carriers of balanced chromosomal rearrangements

Advantages of the NIPT Test

High Accuracy: Detects Down syndrome with over 99% reliability.
Completely Safe: Requires only a blood sample; no risk to mother or baby.
Early Detection: Can be performed as early as 10 weeks.
Determines Gender: Accurately identifies baby’s gender if requested.
Fewer False Positives: Reduces the need for unnecessary invasive tests.
Convenient and Painless: No fasting or preparation needed; just a quick blood draw.

Limitations of the NIPT Test

While NIPT is extremely reliable, it is a screening test, not a diagnostic test.

A positive (high-risk) result suggests increased likelihood but does not confirm an abnormality. Diagnostic confirmation through amniocentesis or chorionic villus sampling (CVS) is required.
NIPT does not detect all genetic diseases, such as single-gene disorders or structural anomalies.
In rare cases, the test may not yield results due to low fetal DNA levels, which is more common in early pregnancies or women with higher BMI. Retesting after 1–2 weeks usually provides a result.
Accuracy may be slightly lower for twin pregnancies compared to single pregnancies.

How Is the NIPT Test Performed?

Before the Test:
Your obstetrician or genetic counselor will explain what the test includes and how to interpret the results. Many Yalova clinics provide teleconsultation or referral to a genetics specialist prior to testing.

During the Test:
A small blood sample is taken from your arm. The procedure is painless, quick, and does not require fasting or special preparation.

After the Test:
The sample is sent to an accredited laboratory for genetic sequencing. Results are delivered within 7–10 days, depending on laboratory workload and test scope.

Understanding the Results

Low-Risk (Negative):
Indicates a very low likelihood of chromosomal abnormalities. Routine prenatal care continues.

High-Risk (Positive):
Indicates an increased probability of a chromosomal abnormality. Diagnostic confirmation with amniocentesis or CVS is advised.

Inconclusive Result:
Occurs when fetal DNA levels are insufficient for accurate analysis. A repeat test after one to two weeks often resolves this issue.

NIPT Test Cost in Yalova

Basic NIPT tests: 12,500 – 14,000 TL
Extended panels: 15,000 – 18,000 TL

Prices vary depending on the type of panel chosen and the laboratory performing the analysis. Some clinics provide expedited services for an additional fee.

Insurance Coverage:
The NIPT test is not covered by Turkey’s Social Security Institution (SGK). However, some private insurance policies may cover part of the cost.

Where to Get the NIPT Test in Yalova

In Yalova, NIPT can be accessed through:

Private obstetrics and gynecology clinics that send samples to certified laboratories
Hospitals with partnerships in genetic diagnostics
Referral from your obstetrician to regional testing centers

These clinics follow strict standards for sample handling and testing to ensure accurate and reliable results.

Comparison with Other Prenatal Tests

Traditional Double and Triple Tests:
These tests are less accurate and have higher false-positive rates compared to NIPT.

Ultrasound (Nuchal Translucency):
Ultrasound remains crucial for assessing fetal anatomy and growth. NIPT complements ultrasound but does not replace it.

Frequently Asked Questions

Is the NIPT test mandatory?
No, it is optional and depends on the family’s preference.

Can NIPT determine the baby’s gender?
Yes, it can accurately identify the baby’s gender from week 10 onward.

Does NIPT replace amniocentesis?
No, NIPT is a screening test. Positive results must be confirmed through diagnostic testing.

Is fasting required before the test?
No fasting or preparation is required.

Can twins be tested?
Yes, but accuracy may be slightly reduced compared to single pregnancies.

How long do results take?
Usually within 7–10 days; some laboratories offer results in 3–5 days.

Final Thoughts

The Fetal DNA (NIPT) Test in Yalova offers a safe, early, and highly accurate way to assess your baby’s genetic health. Even if samples are sent to larger city laboratories, Yalova clinics ensure proper collection and coordination, giving you access to the same quality testing available in major centers.

With no risk to mother or baby, and with the ability to detect key chromosomal abnormalities, NIPT has become a cornerstone of modern prenatal care. For the best results, it should be combined with regular ultrasounds and medical consultations throughout pregnancy.