FETAL DNA (NIPT) TEST IN DİDİM

Safe, Accurate, and Non-Invasive Prenatal Genetic Screening

What Is the NIPT Test?

NIPT (Non-Invasive Prenatal Testing) — also called the Fetal DNA test or cell-free fetal DNA (cffDNA) test — is a modern, safe, and precise method for evaluating your baby’s genetic health during pregnancy. It analyzes small fragments of fetal DNA circulating in the mother’s bloodstream, helping detect chromosomal abnormalities early and without risk.

For information and appointments: +90 542 225 89 12 – Ataşehir / Istanbul

In Didim, NIPT testing is available through private hospitals, gynecology clinics, and partner laboratories that work with accredited genetic centers in Turkey. The test is simple and completely safe — only a blood sample from the mother’s arm is required, with no invasive procedure and no risk to the baby.

How Does the NIPT Test Work?

During pregnancy, fragments of the baby’s DNA pass through the placenta into the mother’s bloodstream. These DNA fragments, known as cell-free fetal DNA, can be analyzed starting from the 10th week of pregnancy.

Using Next Generation Sequencing (NGS) technology, laboratories can assess the number and structure of chromosomes in the sample. This helps identify if the baby has any extra or missing chromosomes, which could cause genetic conditions.

Results are usually available within 7–10 days, although some laboratories provide express options that deliver results in 3–5 days.

What Conditions Can NIPT Detect?

Major Chromosomal Abnormalities

NIPT accurately screens for the most common chromosomal abnormalities:

Down Syndrome (Trisomy 21): Extra chromosome 21; detection accuracy above 99%.
Edwards Syndrome (Trisomy 18): Extra chromosome 18; detection accuracy around 97%.
Patau Syndrome (Trisomy 13): Extra chromosome 13; detection accuracy above 90%.

Sex Chromosome Abnormalities

The test can also detect abnormalities involving sex chromosomes, including:

Turner Syndrome (45,X)
Klinefelter Syndrome (47,XXY)
Triple X Syndrome (47,XXX)
Jacobs Syndrome (47,XYY)

Extended Genetic Panels

Some laboratories that serve the Didim region offer expanded NIPT panels that can detect rare conditions such as DiGeorge, Prader-Willi, and Angelman syndromes. Your doctor can help determine whether this additional testing is necessary.

When Should the NIPT Test Be Performed?

The NIPT test is typically done from the 10th week of pregnancy onward, when there is enough fetal DNA in the mother’s blood for accurate analysis. It can also be performed safely later in pregnancy.

Who Should Consider NIPT?

Although NIPT is suitable for all pregnant women, it is especially recommended for those who:

Are 35 years or older
Have abnormal first-trimester screening results
Conceived through IVF or assisted reproduction
Have a family history of chromosomal abnormalities
Have ultrasound findings suggesting a genetic condition
Wish to avoid invasive diagnostic tests such as amniocentesis
Are carriers of balanced chromosomal rearrangements

Advantages of the NIPT Test

Extremely Accurate: Detects Down syndrome and other trisomies with >99% accuracy.
Completely Safe: Only requires a maternal blood sample; no risk to the baby.
Early Testing: Can be done as early as 10 weeks of pregnancy.
Determines Gender: Can accurately determine the baby’s gender if requested.
Lower False Positives: Reduces unnecessary invasive testing.
Convenient and Quick: Simple blood draw; no fasting or special preparation required.

Limitations of the NIPT Test

While NIPT is highly reliable, it is still a screening test, not a diagnostic test:

A positive (high-risk) result means increased risk but does not confirm the condition; diagnostic confirmation through amniocentesis or CVS is needed.
NIPT does not detect all genetic disorders, such as single-gene conditions or structural anomalies.
In rare cases, the test may fail to yield a result if fetal DNA levels are too low. Retesting after 1–2 weeks typically resolves this issue.
Accuracy is slightly lower in twin pregnancies compared to single pregnancies.

How Is the NIPT Test Performed?

Before the Test:
Your doctor or genetic counselor will explain the test process, what conditions it covers, and what results mean.

During the Test:
A small amount of blood is drawn from your arm. The process is quick, painless, and does not require fasting.

After the Test:
The sample is sent to an accredited genetic laboratory for sequencing and analysis. Results are ready in 7–10 days, and your doctor will review them in detail.

Understanding the Results

Low-Risk (Negative):
Indicates a low probability of chromosomal abnormalities. No further testing is typically needed.

High-Risk (Positive):
Indicates a higher probability of a chromosomal condition. Confirmation with diagnostic testing is recommended.

Inconclusive Result:
If fetal DNA levels are too low, results may be inconclusive. Retesting after one to two weeks usually resolves this.

NIPT Test Cost in Didim

Basic NIPT tests: 12,500 – 14,000 TL
Extended panels: 15,000 – 18,000 TL

The cost varies depending on the test type, laboratory, and turnaround time. Some centers offer express testing for an additional fee.

Insurance Coverage:
The NIPT test is not covered by Turkey’s Social Security Institution (SGK), but some private insurance companies may cover part of the cost.

Where to Get the NIPT Test in Didim

NIPT testing is available in Didim through:

Private obstetrics and gynecology clinics
Hospitals with referral partnerships to national genetic laboratories
IVF and perinatology centers offering prenatal genetic screening

Clinics in Didim typically collect the blood sample and send it to an accredited laboratory for analysis under strict quality standards.

Comparison with Other Prenatal Tests

Traditional Double and Triple Tests:
These conventional tests are less accurate and have higher false-positive rates than NIPT.

Ultrasound (Nuchal Translucency Measurement):
Ultrasound remains essential for evaluating fetal anatomy and growth. NIPT complements ultrasound by providing genetic information but does not replace it.

Frequently Asked Questions

Is the NIPT test mandatory?
No, it’s optional but widely recommended for reassurance about your baby’s health.

Can the test determine the baby’s gender?
Yes, the baby’s gender can be accurately identified from week 10 onward if requested.

Does NIPT replace amniocentesis?
No, NIPT is a screening test. Positive results must be confirmed through diagnostic testing.

Is fasting required?
No fasting or special preparation is needed.

Can twins be tested?
Yes, though accuracy may be slightly lower in twin pregnancies.

When are results available?
Typically within 7–10 days; some labs provide faster results in 3–5 days.

Final Thoughts

The Fetal DNA (NIPT) Test in Didim is a safe, early, and highly accurate method for expectant parents to assess their baby’s genetic health. With professional obstetric care, collaboration with advanced laboratories, and fast results, Didim provides reliable access to modern prenatal testing.

By combining NIPT with regular ultrasound checkups and healthy pregnancy practices, families can enjoy peace of mind and a better understanding of their baby’s health.