FETAL DNA (NIPT) TEST IN ATAŞEHİR

Safe, Accurate, and Non-Invasive Prenatal Genetic Screening

What Is the NIPT Test?

NIPT (Non-Invasive Prenatal Testing), also known as the Fetal DNA test or cell-free fetal DNA (cffDNA) test, is a modern, non-invasive prenatal screening that analyzes fragments of your baby’s DNA circulating in your blood. It provides early and accurate information about the baby’s genetic health, allowing expectant parents to make informed decisions during pregnancy.

For information and appointments: +90 542 225 89 12 – Ataşehir / Istanbul

In Ataşehir, NIPT is available at private hospitals, specialized clinics, and genetic laboratories equipped with the latest sequencing technologies. The test requires only a small blood sample from the mother’s arm, making it completely safe for both mother and baby. No amniocentesis or other invasive procedures are involved.

How Does the NIPT Test Work?

During pregnancy, small fragments of fetal DNA originating from the placenta enter the mother’s bloodstream. These fragments, known as cell-free fetal DNA (cffDNA), can be detected and analyzed through advanced genetic sequencing.

From the 10th week of pregnancy onward, there is enough fetal DNA in the mother’s blood to perform accurate testing. Laboratories in Ataşehir use Next Generation Sequencing (NGS) technology to evaluate the number and structure of chromosomes, identifying any potential abnormalities.

Results are typically available within 7–10 days, though some centers offer expedited results in as little as 3–5 days.

What Can the NIPT Test Detect?

Common Chromosomal Abnormalities

The NIPT test screens for the most frequent chromosomal conditions with very high accuracy:

Down Syndrome (Trisomy 21): Caused by an extra copy of chromosome 21; detection rate exceeds 99%.
Edwards Syndrome (Trisomy 18): Results from an extra chromosome 18; detection accuracy around 97%.
Patau Syndrome (Trisomy 13): Caused by an extra chromosome 13; detection accuracy above 90%.

Sex Chromosome Abnormalities

The test can also detect variations in sex chromosomes, such as:

Turner Syndrome (45,X)
Klinefelter Syndrome (47,XXY)
Triple X (47,XXX)
Jacobs Syndrome (47,XYY)

Extended Genetic Panels

Some genetic laboratories in Ataşehir offer expanded NIPT panels that can screen for rare microdeletion and microduplication syndromes, including DiGeorge, Prader-Willi, and Angelman syndromes. Your doctor can advise whether an extended panel is appropriate for your case.

When Should the NIPT Test Be Performed?

The NIPT test can be performed as early as the 10th week of pregnancy. At this point, there is sufficient fetal DNA in the maternal bloodstream for reliable results.

The test remains valid and safe throughout pregnancy, including the second and third trimesters.

Who Should Consider NIPT?

Although NIPT is suitable for all pregnant women, it is especially recommended for:

Women aged 35 years or older
Those with abnormal first-trimester screening results
Pregnancies achieved via IVF (in vitro fertilization)
Families with a history of genetic disorders
Expectant mothers with ultrasound findings suggesting abnormalities
Parents wishing to avoid invasive diagnostic procedures like amniocentesis
Carriers of known balanced chromosomal rearrangements

Advantages of the NIPT Test

High Accuracy: Over 99% detection rate for Down syndrome and high accuracy for other trisomies.
Completely Safe: Requires only a maternal blood sample — no risk to baby or mother.
Early Detection: Can be performed as early as week 10.
Gender Determination: Baby’s sex can be identified at the same time.
Fewer False Positives: Reduces unnecessary invasive tests and related stress.
Quick and Painless: No fasting, simple blood draw, fast results.

Limitations of the NIPT Test

Screening, Not Diagnostic: A high-risk result means increased likelihood but not confirmation. Diagnostic tests like amniocentesis or CVS are required for confirmation.
Not All Disorders Detected: NIPT cannot detect single-gene mutations, structural malformations, or neural tube defects.
Possible Inconclusive Results: Rarely, if fetal DNA levels are too low, results may be inconclusive. Retesting is often successful after 1–2 weeks.
Multiple Pregnancies: NIPT is suitable for twin pregnancies, though accuracy may be slightly reduced. It is not recommended for triplets or higher-order multiples.

How Is the Test Performed?

Before the Test:
Your doctor or genetic counselor will discuss what the test screens for, what the results mean, and what follow-up steps may be needed. Many clinics in Ataşehir offer pre-test counseling.

During the Test:
A simple blood sample is taken from your arm. The procedure takes only a few minutes and requires no fasting or preparation.

After the Test:
The sample is analyzed in an accredited genetic laboratory. Results are typically ready within a week and shared with your doctor for interpretation.

Understanding the Results

Low Risk (Negative):
Indicates that your baby is unlikely to have any of the tested chromosomal abnormalities. Routine prenatal care continues.

High Risk (Positive):
Indicates an increased chance of a chromosomal abnormality. Diagnostic confirmation via amniocentesis or CVS is recommended.

Inconclusive Result:
May occur if there is insufficient fetal DNA in the blood sample. Most clinics offer free or discounted retesting.

NIPT Test Cost in Ataşehir

Basic NIPT tests: 12,500 – 14,000 TL
Extended panels: 15,000 – 18,000 TL

Prices vary slightly depending on the laboratory and the scope of the test. Some clinics offer express processing at an additional cost.

Insurance Coverage:
The NIPT test is not currently covered by Turkey’s Social Security Institution (SGK). However, some private health insurance plans may reimburse part of the cost.

Where to Get NIPT in Ataşehir

NIPT is available at:

Private hospitals and maternity clinics
Specialized genetic laboratories
Women’s health centers with prenatal care services

All major facilities in Ataşehir adhere to international standards and use certified genetic testing methods for reliable and accurate results.

Comparison with Other Prenatal Tests

Traditional Screening Tests (Double and Triple Tests):
Older methods have lower accuracy and higher false-positive rates compared to NIPT.

Ultrasound (Nuchal Translucency):
Ultrasound remains crucial for monitoring fetal development and structural anomalies. NIPT complements ultrasound by providing genetic information rather than replacing it.

Frequently Asked Questions

Is the NIPT test mandatory?
No, it’s an optional prenatal screening.

Can NIPT determine the baby’s gender?
Yes, it can identify gender with nearly 100% accuracy as early as 10 weeks.

Does NIPT replace amniocentesis?
No, NIPT is a screening test. Positive results must be confirmed with diagnostic testing.

Is fasting required?
No fasting is needed.

Can twins be tested?
Yes, NIPT works for twin pregnancies, though accuracy is slightly reduced.

How long do results take?
Typically 7–10 days; expedited results may be available.

Final Thoughts

The Fetal DNA (NIPT) Test in Ataşehir provides expectant parents with safe, early, and highly accurate insights into their baby’s genetic health. With no risk to mother or baby and results available as early as the 10th week of pregnancy, NIPT has become a cornerstone of modern prenatal care.

Ataşehir’s advanced medical centers and experienced obstetricians ensure that this test is performed according to international standards, providing reliable results and peace of mind for families.

Regular prenatal checkups, detailed ultrasounds, and genetic counseling remain vital to ensuring a healthy pregnancy journey.