FETAL DNA (NIPT) TEST IN BAKIRKÖY

Safe, Accurate, and Non-Invasive Prenatal Screening

What Is the NIPT Test?

NIPT (Non-Invasive Prenatal Testing), also called the Fetal DNA test or cell-free fetal DNA (cffDNA) test, is a highly advanced prenatal screening method that analyzes fragments of your baby’s DNA found in the mother’s blood. It provides early, accurate, and risk-free information about your baby’s genetic health.

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In Bakırköy, this test is available at numerous private hospitals, women’s health centers, and specialized genetic laboratories. NIPT requires only a small blood sample taken from the mother’s arm, making it entirely safe for both mother and baby. There is no risk of miscarriage or harm, unlike invasive diagnostic procedures such as amniocentesis.

How Does the NIPT Test Work?

During pregnancy, tiny fragments of fetal DNA pass from the placenta into the mother’s bloodstream. These are known as cell-free fetal DNA (cffDNA). Beginning around the 10th week of pregnancy, the amount of fetal DNA circulating in the mother’s blood becomes sufficient to allow accurate analysis.

In Bakırköy’s advanced genetic laboratories, specialists analyze these DNA fragments using Next Generation Sequencing (NGS) technology. This method assesses the baby’s chromosomes to identify any abnormalities. The test can also determine the baby’s gender if desired.

Results are typically ready within 7–10 days, and some centers in Bakırköy offer express processing options with results available in 3–5 days.

What Conditions Can NIPT Detect?

Major Chromosomal Abnormalities

NIPT primarily screens for the most common chromosomal conditions, including:

Down Syndrome (Trisomy 21): Caused by an extra copy of chromosome 21; detection rate over 99%.
Edwards Syndrome (Trisomy 18): Caused by an extra chromosome 18; detection accuracy about 97%.
Patau Syndrome (Trisomy 13): Caused by an extra chromosome 13; detection accuracy above 90%.

Sex Chromosome Abnormalities

NIPT can also detect anomalies involving the sex chromosomes, such as:

Turner Syndrome (45,X)
Klinefelter Syndrome (47,XXY)
Triple X Syndrome (47,XXX)
Jacobs Syndrome (47,XYY)

Extended Genetic Panels

Some genetic laboratories in Bakırköy offer expanded NIPT panels that screen for additional chromosomal microdeletions and microduplications, such as DiGeorge, Prader-Willi, and Angelman syndromes. Your doctor will help determine whether an extended panel is necessary based on your personal and family history.

When Should the NIPT Test Be Done?

The NIPT test can be performed from the 10th week of pregnancy onward. At this stage, there is enough fetal DNA in the mother’s bloodstream to obtain reliable results. The test remains safe and accurate throughout pregnancy.

Who Should Consider NIPT?

Although NIPT can be offered to all pregnant women, it is particularly recommended for:

Women aged 35 years or older
Those who receive high-risk results from first-trimester screening tests
Expectant mothers with a family history of genetic disorders
Pregnancies achieved through IVF (in vitro fertilization)
Ultrasound findings suggesting chromosomal abnormalities
Parents who prefer to avoid invasive diagnostic tests
Carriers of balanced chromosomal rearrangements

Advantages of the NIPT Test

Exceptional Accuracy: Over 99% detection for Down syndrome and above 95% for other trisomies.
Completely Safe: Requires only a blood sample; no risk of miscarriage.
Early Detection: Can be performed as early as 10 weeks.
Determines Gender: Baby’s gender can be identified early with high accuracy.
Low False Positive Rate: Reduces unnecessary invasive procedures.
Quick and Convenient: Simple blood draw, no fasting, no special preparation.

Limitations of the NIPT Test

While NIPT is a powerful tool, it is still a screening test, not a diagnostic one.

A high-risk (positive) result does not confirm a diagnosis; confirmatory testing via amniocentesis or CVS is required.
NIPT does not detect all genetic conditions (e.g., single-gene disorders or neural tube defects).
In a small number of cases, the test may not yield a result due to insufficient fetal DNA. This is more common in early pregnancies or mothers with higher BMI.
Twin pregnancies can be tested, though accuracy may be slightly lower; the test is not recommended for triplets or higher multiples.

How Is the NIPT Test Performed?

Before the Test:
Your doctor or genetic counselor will explain what the test can detect and how to interpret results. Many centers in Bakırköy offer counseling before and after testing.

During the Test:
A small blood sample is drawn from your arm — the process is quick and painless. No fasting or preparation is required.

After the Test:
The sample is analyzed in a certified laboratory. Results are usually available in 7–10 days, and your doctor will contact you to discuss them.

Understanding the Results

Low Risk (Negative):
Indicates a low probability of chromosomal abnormalities. Routine prenatal care can continue as usual.

High Risk (Positive):
Indicates an increased risk for chromosomal conditions. Diagnostic confirmation with amniocentesis or CVS is recommended.

Inconclusive Result:
May occur when fetal DNA levels are insufficient. A repeat test after 1–2 weeks often resolves the issue.

NIPT Test Cost in Bakırköy

Basic NIPT tests: 12,500 – 14,000 TL
Extended panels: 15,000 – 18,000 TL

Costs vary depending on the laboratory, the scope of testing, and result delivery time. Some clinics charge slightly higher prices for rapid turnaround or extended analysis.

Insurance Coverage:
NIPT is not covered by Turkey’s Social Security Institution (SGK). However, some private health insurance policies may reimburse partial or full costs.

Where to Get NIPT in Bakırköy

You can undergo NIPT testing at:

Private hospitals and obstetrics clinics
Specialized genetic laboratories
University hospitals with prenatal testing departments

Centers in Bakırköy are equipped with certified technology and experienced professionals, ensuring international testing standards.

Comparison with Other Prenatal Tests

Traditional Double and Triple Tests:
These screening tests remain common but are less accurate and have higher false-positive rates compared to NIPT.

Ultrasound (Nuchal Translucency):
Ultrasound examinations remain crucial for fetal anatomy assessment. NIPT complements ultrasound by providing genetic information rather than replacing it.

Frequently Asked Questions

Is NIPT mandatory?
No, it is optional and based on parental preference.

Can the test reveal baby’s gender?
Yes, with nearly 100% accuracy as early as week 10.

Does NIPT replace amniocentesis?
No, it’s a screening test; diagnostic procedures are still required for confirmation.

Is fasting required?
No, fasting or preparation is not necessary.

Can twins be tested?
Yes, though accuracy may be slightly lower than for single pregnancies.

When will results be available?
Usually within 7–10 days; some labs offer express results in 3–5 days.

Final Thoughts

The Fetal DNA (NIPT) Test in Bakırköy represents a major advancement in modern prenatal care. It offers expecting parents early, accurate, and completely risk-free insights into their baby’s genetic health.

With Bakırköy’s well-equipped medical infrastructure and experienced obstetric specialists, you can access reliable prenatal testing in a comfortable, safe environment.

Regular ultrasounds, healthy lifestyle choices, and continuous communication with your doctor remain essential throughout pregnancy.