FETAL DNA (NIPT) TEST IN TAKSİM

Safe, Accurate, and Non-Invasive Prenatal Genetic Screening

What Is the NIPT Test?

NIPT (Non-Invasive Prenatal Testing), also called the Fetal DNA test or cell-free fetal DNA (cffDNA) test, is a revolutionary prenatal screening method that provides early and reliable information about your baby’s genetic health. The test analyzes small fragments of fetal DNA circulating in the mother’s bloodstream to identify possible chromosomal abnormalities — safely and without any risk to the baby.

For information and appointments: +90 542 225 89 12 – Ataşehir / Istanbul

In Taksim, many private hospitals, clinics, and genetic diagnostic centers offer NIPT testing using internationally approved laboratory standards. The procedure involves only a simple blood draw from the mother’s arm, with no risk of miscarriage or harm to the baby. This makes NIPT one of the safest and most preferred prenatal screening tests worldwide.

How Does the NIPT Test Work?

During pregnancy, fragments of the baby’s DNA — known as cell-free fetal DNA (cffDNA) — enter the mother’s bloodstream through the placenta. These DNA fragments can be analyzed from the 10th week of pregnancy onward to provide accurate information about the baby’s chromosomes.

In Taksim’s advanced medical centers, samples are processed using Next Generation Sequencing (NGS) technology, which evaluates the number and structure of chromosomes. This process helps identify chromosomal abnormalities such as Down syndrome, Edwards syndrome, and Patau syndrome.

Test results are typically available within 7–10 days, and some specialized laboratories in Taksim offer express options with results in as little as 3–5 days.

What Conditions Can NIPT Detect?

Common Chromosomal Abnormalities

NIPT primarily screens for three major chromosomal conditions:

Down Syndrome (Trisomy 21): The most common chromosomal abnormality; detection rate over 99%.
Edwards Syndrome (Trisomy 18): Caused by an extra chromosome 18; detection accuracy around 97%.
Patau Syndrome (Trisomy 13): Caused by an extra chromosome 13; detection accuracy above 90%.

Sex Chromosome Abnormalities

NIPT also detects variations involving the sex chromosomes, including:

Turner Syndrome (45,X)
Klinefelter Syndrome (47,XXY)
Triple X Syndrome (47,XXX)
Jacobs Syndrome (47,XYY)

Extended Genetic Panels

Some advanced laboratories in Taksim provide extended NIPT panels capable of detecting rarer microdeletion and microduplication syndromes such as DiGeorge, Prader-Willi, and Angelman syndromes. Your doctor can advise whether these extended panels are appropriate for your case.

When Should the NIPT Test Be Done?

The NIPT test can be performed from the 10th week of pregnancy onward, once the fetal DNA concentration in maternal blood is sufficient for analysis. It can also be performed later in pregnancy, even in the second and third trimesters, with the same reliability and accuracy.

Who Should Consider NIPT?

Although NIPT is suitable for all pregnant women, it is especially recommended for:

Women aged 35 years or older
Pregnancies with abnormal results from earlier screening tests
Women who conceived through IVF (in vitro fertilization)
Families with a history of genetic disorders
Expectant mothers with ultrasound findings suggesting chromosomal abnormalities
Parents who prefer to avoid invasive procedures such as amniocentesis or CVS
Carriers of balanced chromosomal rearrangements

Advantages of the NIPT Test

Highly Accurate: Over 99% accuracy for Down syndrome and other major trisomies.
Completely Safe: Requires only a blood sample; no risk to baby or mother.
Early Detection: Can be done as early as the 10th week of pregnancy.
Gender Determination: Accurately reveals the baby’s gender if requested.
Less Anxiety: Fewer false positives and unnecessary invasive tests.
Simple and Painless: No fasting or preparation required; just a short blood draw.

Limitations of the NIPT Test

While NIPT is highly reliable, it remains a screening test — not a diagnostic one.

A positive (high-risk) result indicates an increased likelihood of a chromosomal condition but does not confirm it. Diagnostic tests such as amniocentesis or CVS are necessary for confirmation.
NIPT cannot detect all genetic disorders, such as single-gene conditions or neural tube defects.
Occasionally, the test may fail to yield results if fetal DNA levels are too low, more common in early pregnancies or mothers with higher body mass index (BMI).
The test can be performed for twin pregnancies, but accuracy is slightly lower than for single pregnancies.

How Is the NIPT Test Performed?

Before the Test:
Your obstetrician or genetic counselor will explain the test, its benefits, and its limitations. In Taksim, most clinics offer counseling before and after the procedure.

During the Test:
A simple blood sample is collected from your arm. The process takes just a few minutes and does not require fasting or special preparation.

After the Test:
The sample is analyzed in a specialized genetic laboratory. Results are available within 7–10 days, depending on the laboratory’s capacity and test type.

Understanding the Results

Low-Risk (Negative):
Indicates a low probability of chromosomal abnormalities. Routine prenatal care continues as normal.

High-Risk (Positive):
Indicates an increased chance of an abnormality. Confirmatory testing (amniocentesis or CVS) is recommended for a definitive diagnosis.

Inconclusive:
Occurs if the sample contains insufficient fetal DNA. Retesting after 1–2 weeks usually resolves the issue.

NIPT Test Cost in Taksim

Basic NIPT tests: 12,500 – 14,000 TL
Extended panels: 15,000 – 18,000 TL

Prices vary depending on the testing laboratory, scope of analysis, and turnaround time. Some facilities offer premium same-week results for an additional fee.

Insurance Coverage:
The NIPT test is not covered by Turkey’s Social Security Institution (SGK), though some private insurance policies may reimburse a portion of the cost.

Where to Get the NIPT Test in Taksim

You can take the NIPT test at:

Private hospitals with obstetrics and gynecology units
Specialized genetic laboratories
University hospitals with advanced prenatal care units

Most Taksim-based facilities operate with accredited labs and experienced specialists, following international testing standards.

Comparison with Other Prenatal Tests

Double and Triple Screening Tests:
These traditional screening methods are still in use but have lower accuracy and higher false-positive rates than NIPT.

Ultrasound (Nuchal Translucency Measurement):
Ultrasound remains a vital tool for evaluating fetal development and anatomy. NIPT complements ultrasound by adding genetic insight but does not replace it.

Frequently Asked Questions

Is NIPT mandatory?
No, it’s an optional test based on parental choice.

Can the test determine my baby’s gender?
Yes, with nearly 100% accuracy as early as week 10.

Does NIPT replace amniocentesis?
No, it is a screening test; diagnostic tests are still needed for confirmation.

Is fasting required?
No fasting or special preparation is needed.

Can twins be tested?
Yes, though accuracy is slightly lower compared to single pregnancies.

When will results be ready?
Usually within 7–10 days; some labs provide express results in 3–5 days.

Final Thoughts

The Fetal DNA (NIPT) Test in Taksim offers expectant families a safe, non-invasive, and highly accurate way to learn about their baby’s genetic health early in pregnancy. With advanced laboratories, expert gynecologists, and reliable testing facilities in the Taksim area, families can access world-class prenatal care close to home.

By combining NIPT with regular ultrasounds, healthy lifestyle habits, and ongoing communication with your doctor, you can ensure a healthy and informed pregnancy journey.